Search results for "Relaxin · Obstructive sleep apnea · Metalloproteinase · Vascular endothelial growth factor"

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Relaxin in Obstructive Sleep Apnea: Relationship with Blood Pressure and Inflammatory Mediators

2015

<b><i>Background:</i></b> Obstructive sleep apnea (OSA) is associated with nocturnal intermittent hypoxia, which may be responsible for increased circulating levels of vascular endothelial growth factor (VEGF) and inflammatory mediators, such as metalloproteinases (MMPs), and which contributes to the pathogenesis of systemic hypertension. Why some OSA patients remain normotensive is poorly understood. Relaxin-2, a pregnancy hormone, may sometimes circulate in men and could increase in hypoxic conditions. It exerts a vasodilatory activity and can modulate the release of molecules, such as MMPs and VEGF. <b><i>Objectives:</i></b> The objective o…

AdultMaleVascular Endothelial Growth Factor APulmonary and Respiratory Medicinemedicine.medical_specialtyAmbulatory blood pressurePolysomnographyBlood PressurePolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineRelaxin · Obstructive sleep apnea · Metalloproteinase · Vascular endothelial growth factorInterquartile rangeInternal medicineRespiratory disturbance indexmedicineHumansHypoxiaInflammationSleep Apnea ObstructiveTissue Inhibitor of Metalloproteinase-2Tissue Inhibitor of Metalloproteinase-1medicine.diagnostic_testbusiness.industryRelaxinSleep apneaTissue Inhibitor of MetalloproteinasesIntermittent hypoxiaMiddle Agedmedicine.diseaseMatrix MetalloproteinasesObstructive sleep apneaEndocrinologyBlood pressureMatrix Metalloproteinase 9030228 respiratory systemHypertensionMatrix Metalloproteinase 2Inflammation MediatorsbusinessRespiration
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